Finland's Galapagos: Founder effect, drift, and isolation in the inheritance of susceptibility alleles
Identifieur interne : 002243 ( Main/Exploration ); précédent : 002242; suivant : 002244Finland's Galapagos: Founder effect, drift, and isolation in the inheritance of susceptibility alleles
Auteurs : Tom Campbell [Finlande] ; Daria Osipova [Finlande] ; Seppo K Hkönen [Finlande]Source :
- Behavioral and Brain Sciences [ 0140-525X ] ; 2006-08.
Abstract
The target article excludes ancestral neutrality as a cause for the inheritance of schizophrenia, with an argument relating to selection against a single allele in the Finnish population. However, drift would predominate over selection within subisolates of the Finnish population. Comparisons of subisolates with heterogeneous populations may provide clues to the endophenotypic structure of complex polygenetic heritable mental disorders.
Url:
DOI: 10.1017/S0140525X06279093
Affiliations:
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However, drift would predominate over selection within subisolates of the Finnish population. Comparisons of subisolates with heterogeneous populations may provide clues to the endophenotypic structure of complex polygenetic heritable mental disorders.</div></front></TEI><affiliations><list><country><li>Finlande</li></country><region><li>Uusimaa</li></region><settlement><li>Helsinki</li></settlement><orgName><li>Université d'Helsinki</li></orgName></list><tree><country name="Finlande"><region name="Uusimaa"><name sortKey="Campbell, Tom" sort="Campbell, Tom" uniqKey="Campbell T" first="Tom" last="Campbell">Tom Campbell</name></region><name sortKey="Campbell, Tom" sort="Campbell, Tom" uniqKey="Campbell T" first="Tom" last="Campbell">Tom Campbell</name><name sortKey="K Hkonen, Seppo" sort="K Hkonen, Seppo" uniqKey="K Hkonen S" first="Seppo" last="K Hkönen">Seppo K Hkönen</name><name sortKey="K Hkonen, Seppo" sort="K Hkonen, Seppo" uniqKey="K Hkonen S" first="Seppo" last="K Hkönen">Seppo K Hkönen</name><name sortKey="Osipova, Daria" sort="Osipova, Daria" uniqKey="Osipova D" first="Daria" last="Osipova">Daria Osipova</name><name sortKey="Osipova, Daria" sort="Osipova, Daria" uniqKey="Osipova D" first="Daria" last="Osipova">Daria Osipova</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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